About   Help   FAQ
Symbol
Name
ID
Opa1
OPA1, mitochondrial dynamin like GTPase
MGI:1921393
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Hypothyroidism
Hypogonadism
Disease(s) Associated with OPA1
optic atrophy

Mouse Phenotypes
decreased pancreatic beta cell proliferation
abnormal pancreatic beta cell morphology
decreased pancreatic beta cell number
small pancreatic islets
abnormal pancreatic beta cell physiology
decreased insulin secretion
Availability Mouse Genotype
Opa1tm1.1Hise/Opa1tm1.2Hise
Tg(Ins2-cre)25Mgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory